Proteins
  2. Proteins (PIs)
  3. Proteins details
PINIR_50 [A0A2G3AW40]  : Proteinase inhibitor type-2

200Length

Capsicum chinenseSpecie

BC332_32641Gene Name

21647Mass

5Domain Count

Sequence :
     FASTA
MAVPKEVSFP ACLLVLGMFV IANAVELGDD IKVCTMECGN FAYGICPRSE GSPICTNCCS GYKGCNYYSA 70
NGTFICEGRS DPRKTNICTQ HCDPRVAYSK CPRSGGNTII KHTGCTTCCT GYKGCYYFGH DGKFVCEGQS 140
SEPRACTLEC DPKVAYMTCP SSGSTKLTRI CFNCCTARVQ GCKLYGHDES LLCTGDPRNY 200
SIGNAL PEPTIDE
SEQUENCE Position
MAVPKEVSFPACLLVLGMFVIANA
 1 ↔ 24
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
IRD-14
113 - 162 50
IRD-43
53 - 104 52
IRD-294
86 - 138 53
IRD-414
144 - 195 52
IRD-692
32 - 78 47
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
6.95299999999999
6 -7.5 -16.4
CROSS REFERENCES
Uniprot Interpro Id Pfam Id EMBL
A0A2G3AW40 View PI in InterPro
IPR003465 		View protein in Pfam
PF02428		 MCIT02000041
REFERENCES
PubMed ID:     29089032    |
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-19 CTMEC Unknown 35 - 39
RL-25 CTQHC Unknown 89 - 93
RL-25 CTQHC Unknown 89 - 93
RL-9 CTLEC Chymotrypsin 147 - 151
RL-9 CTLEC Chymotrypsin 147 - 151
GO TERMS
Molecular Function Cellular Component Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867) None None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
No Records Found
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-14 113 - 162 CTLEC 146 - 150 - H+L Type (Type-III)
IRD-43 53 - 104 CTQHC 88 - 92 DPRKT 81 - 85 H-L Type (Type-I)
IRD-294 86 - 138 CTQHC 88 - 92 GGNTI 105 - 109 L-H Type (Type-II)
IRD-414 144 - 195 CTLEC 146 - 150 GSTKL 163 - 167 L-H Type (Type-II)
IRD-692 32 - 78 CTMEC 34 - 38 - H+L Type (Type-III)
TGCTTCCTGYKGCYYFGHDGKFVCEGQSSEPRACTLECDPKVAYMTCPSS
CTLEC
H+L Type (Type-III)
3,38 ; 6,24 ; 7,34 ; 13,47
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
T G C T T C C T G Y K G C Y Y F G H D G K F V C E G Q S S E P R A C T L E C D P K V A Y M T C P S S


PICTNCCSGYKGCNYYSANGTFICEGRSDPRKTNICTQHCDPRVAYSKCPRS
CTQHC
DPRKT
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
P I C T N C C S G Y K G C N Y Y S A N G T F I C E G R S D P R K T N I C T Q H C D P R V A Y S K C P R S


NICTQHCDPRVAYSKCPRSGGNTIIKHTGCTTCCTGYKGCYYFGHDGKFVCEG
CTQHC
GGNTI
L-H Type (Type-II)
3,33 ; 7,34 ; 16,30 ; 40,51
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53
N I C T Q H C D P R V A Y S K C P R S G G N T I I K H T G C T T C C T G Y K G C Y Y F G H D G K F V C E G


RACTLECDPKVAYMTCPSSGSTKLTRICFNCCTARVQGCKLYGHDESLLCTG
CTLEC
GSTKL
L-H Type (Type-II)
3,28 ; 7,32 ; 16,39 ; 31,50
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
R A C T L E C D P K V A Y M T C P S S G S T K L T R I C F N C C T A R V Q G C K L Y G H D E S L L C T G


KVCTMECGNFAYGICPRSEGSPICTNCCSGYKGCNYYSANGTFICEG
CTMEC
H+L Type (Type-III)
3,28 ; 7,34 ; 15,24 ; 27,45
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47
K V C T M E C G N F A Y G I C P R S E G S P I C T N C C S G Y K G C N Y Y S A N G T F I C E G


DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-14
 113 - 162 50
IRD-43
 53 - 104 52
IRD-294
 86 - 138 53
IRD-414
 144 - 195 52
IRD-692
 32 - 78 47
Amino Acid Count % by Frequency
Alanine 10 5
Cysteine 25 12.5
Aspartic acid 8 4
Glutamic acid 9 4.5
Phenylalanine 7 3.5
Glycine 21 10.5
Histidine 4 2
Isoleucine 9 4.5
Lysine 11 5.5
Leucine 9 4.5
Methionine 4 2
Asparagine 9 4.5
Proline 11 5.5
Glutamine 3 1.5
Arginine 9 4.5
Serine 14 7
Threonine 16 8
Valine 10 5
Tryptophan 0 0
Tyrosine 11 5.5