Proteins
  2. Proteins (PIs)
  3. Proteins details
PINIR_54 [A0A2G3AT14]  : Proteinase inhibitor type-2

262Length

Capsicum chinenseSpecie

BC332_33707Gene Name

28625Mass

7Domain Count

Sequence :
     FASTA
MAVPKEVSFL ASLLVLGILL LHVDAKACSQ RNAKEPICTN CCAGRKGCNY YSADGTFICE GESDPKNPKP 70
CTLNCDPRIF YSKCPRSEGN AENRICTNCC AGRKGCNYYS ADGTFICEGE SDPKNPKACP RNCDPRIFYS 140
KCPRSEGNTE NRICTNCCAG RKGCNYYSAD GTFICEGESD PNNPKPCTLN CDPRIFYSKC PRSEASAEQP 210
ICTNCCAGLK GCNYYNADGT FICEGESDPN HPKACPKNCD PNIAYSLCLY EK 262
SIGNAL PEPTIDE
SEQUENCE Position
MAVPKEVSFLASLLVLGILLLHVDA
 1 ↔ 25
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
IRD-122
152 - 203 52
IRD-143
210 - 261 52
IRD-231
94 - 145 52
IRD-256
36 - 87 52
IRD-444
185 - 235 51
IRD-513
127 - 177 51
IRD-551
69 - 119 51
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
6.466
3.4 -12.9 -24.8
CROSS REFERENCES
Uniprot Interpro Id Pfam Id EMBL
A0A2G3AT14 View PI in InterPro
IPR003465 		View protein in Pfam
PF02428		 MCIT02000198
REFERENCES
PubMed ID:     29089032    |
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-1 CPRNC Trypsin 130 - 134
RL-1 CPRNC Trypsin 130 - 134
RL-11 CPKNC Trypsin 246 - 250
RL-3 CTLNC Chymotrypsin 72 - 76
RL-3 CTLNC Chymotrypsin 72 - 76
RL-3 CTLNC Chymotrypsin 188 - 192
RL-3 CTLNC Chymotrypsin 188 - 192
GO TERMS
Molecular Function Cellular Component Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867) None None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
No Records Found
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-122 152 - 203 CTLNC 187 - 191 DPNNP 180 - 184 H-L Type (Type-I)
IRD-143 210 - 261 CPKNC 245 - 249 DPNHP 238 - 242 H-L Type (Type-I)
IRD-231 94 - 145 CPRNC 129 - 133 DPKNP 122 - 126 H-L Type (Type-I)
IRD-256 36 - 87 CTLNC 71 - 75 DPKNP 64 - 68 H-L Type (Type-I)
IRD-444 185 - 235 CTLNC 187 - 191 EASAE 204 - 208 L-H Type (Type-II)
IRD-513 127 - 177 CPRNC 129 - 133 EGNTE 146 - 150 L-H Type (Type-II)
IRD-551 69 - 119 CTLNC 71 - 75 EGNAE 88 - 92 L-H Type (Type-II)
RICTNCCAGRKGCNYYSADGTFICEGESDPNNPKPCTLNCDPRIFYSKCPRS
CTLNC
DPNNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
R I C T N C C A G R K G C N Y Y S A D G T F I C E G E S D P N N P K P C T L N C D P R I F Y S K C P R S


PICTNCCAGLKGCNYYNADGTFICEGESDPNHPKACPKNCDPNIAYSLCLYE
CPKNC
DPNHP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
P I C T N C C A G L K G C N Y Y N A D G T F I C E G E S D P N H P K A C P K N C D P N I A Y S L C L Y E


RICTNCCAGRKGCNYYSADGTFICEGESDPKNPKACPRNCDPRIFYSKCPRS
CPRNC
DPKNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
R I C T N C C A G R K G C N Y Y S A D G T F I C E G E S D P K N P K A C P R N C D P R I F Y S K C P R S


PICTNCCAGRKGCNYYSADGTFICEGESDPKNPKPCTLNCDPRIFYSKCPRS
CTLNC
DPKNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
P I C T N C C A G R K G C N Y Y S A D G T F I C E G E S D P K N P K P C T L N C D P R I F Y S K C P R S


KPCTLNCDPRIFYSKCPRSEASAEQPICTNCCAGLKGCNYYNADGTFICEG
CTLNC
EASAE
L-H Type (Type-II)
3,28 ; 7,32 ; 16,38 ; 31,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
K P C T L N C D P R I F Y S K C P R S E A S A E Q P I C T N C C A G L K G C N Y Y N A D G T F I C E G


KACPRNCDPRIFYSKCPRSEGNTENRICTNCCAGRKGCNYYSADGTFICEG
CPRNC
EGNTE
L-H Type (Type-II)
3,28 ; 7,32 ; 16,38 ; 31,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
K A C P R N C D P R I F Y S K C P R S E G N T E N R I C T N C C A G R K G C N Y Y S A D G T F I C E G


KPCTLNCDPRIFYSKCPRSEGNAENRICTNCCAGRKGCNYYSADGTFICEG
CTLNC
EGNAE
L-H Type (Type-II)
3,28 ; 7,32 ; 16,38 ; 31,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
K P C T L N C D P R I F Y S K C P R S E G N A E N R I C T N C C A G R K G C N Y Y S A D G T F I C E G


DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-122
 152 - 203 52
IRD-143
 210 - 261 52
IRD-231
 94 - 145 52
IRD-256
 36 - 87 52
IRD-444
 185 - 235 51
IRD-513
 127 - 177 51
IRD-551
 69 - 119 51
Amino Acid Count % by Frequency
Alanine 19 7.25
Cysteine 33 12.6
Aspartic acid 13 4.96
Glutamic acid 17 6.49
Phenylalanine 8 3.05
Glycine 19 7.25
Histidine 2 0.76
Isoleucine 13 4.96
Lysine 18 6.87
Leucine 12 4.58
Methionine 1 0.38
Asparagine 24 9.16
Proline 22 8.4
Glutamine 2 0.76
Arginine 13 4.96
Serine 18 6.87
Threonine 11 4.2
Valine 4 1.53
Tryptophan 0 0
Tyrosine 13 4.96