Proteins
  2. Proteins (PIs)
  3. Proteins details
PINIR_58 [A0A2G3AW51]  : Proteinase inhibitor type-2

197Length

Capsicum chinenseSpecie

BC332_32640Gene Name

21658Mass

5Domain Count

Sequence :
     FASTA
MAAHKEVSFL TYLLVLGLMF LLPPKPCTKE CGNFAYGICP RSEGSPKNPI CTTCCAGYKG CYYYDANGKL 70
ICEGQSDPRK PNKHCSRNCD SKIAYSKCPG RSEGKTIIKP TGCTTCCTGY KGCYYYGKDD KFVCEGESIE 140
PRVCTQECDP RVAYMTCPSD GSTKHTRICE NCCTAKPGCK LYDRNGSQLC TGDPKNH 197
SIGNAL PEPTIDE
SEQUENCE Position
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
IRD-30
111 - 160 50
IRD-68
49 - 101 53
IRD-283
142 - 192 51
IRD-472
25 - 74 50
IRD-503
83 - 136 54
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
7.447
11.1 -2.2 -11.3
CROSS REFERENCES
Uniprot Interpro Id Pfam Id EMBL
A0A2G3AW51 View PI in InterPro
IPR003465 		View protein in Pfam
PF02428		 MCIT02000041
REFERENCES
PubMed ID:     29089032    |
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-10 CTKEC Trypsin 28 - 32
RL-18 CTQEC Unknown 145 - 149
RL-18 CTQEC Unknown 145 - 149
RL-22 CSRNC Trypsin 86 - 90
RL-22 CSRNC Trypsin 86 - 90
GO TERMS
Molecular Function Cellular Component Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867) integral component of membrane (GO:0016021) None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
No Records Found
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-30 111 - 160 CTQEC 144 - 148 - H+L Type (Type-III)
IRD-68 49 - 101 CSRNC 85 - 89 DPRKP 77 - 81 H-L Type (Type-I)
IRD-283 142 - 192 CTQEC 144 - 148 - H+L Type (Type-III)
IRD-472 25 - 74 CTKEC 27 - 31 EGSPK 43 - 47 L-H Type (Type-II)
IRD-503 83 - 136 CSRNC 85 - 89 EGKTI 103 - 107 L-H Type (Type-II)
TGCTTCCTGYKGCYYYGKDDKFVCEGESIEPRVCTQECDPRVAYMTCPSD
CTQEC
H+L Type (Type-III)
3,38 ; 6,24 ; 7,34 ; 13,47
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
T G C T T C C T G Y K G C Y Y Y G K D D K F V C E G E S I E P R V C T Q E C D P R V A Y M T C P S D


PICTTCCAGYKGCYYYDANGKLICEGQSDPRKPNKHCSRNCDSKIAYSKCPGR
CSRNC
DPRKP
H-L Type (Type-I)
3,41 ; 6,24 ; 7,37 ; 13,50
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53
P I C T T C C A G Y K G C Y Y Y D A N G K L I C E G Q S D P R K P N K H C S R N C D S K I A Y S K C P G R


RVCTQECDPRVAYMTCPSDGSTKHTRICENCCTAKPGCKLYDRNGSQLCTG
CTQEC
H+L Type (Type-III)
3,32 ; 7,38 ; 16,28 ; 31,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
R V C T Q E C D P R V A Y M T C P S D G S T K H T R I C E N C C T A K P G C K L Y D R N G S Q L C T G


KPCTKECGNFAYGICPRSEGSPKNPICTTCCAGYKGCYYYDANGKLICEG
CTKEC
EGSPK
L-H Type (Type-II)
3,27 ; 7,31 ; 15,37 ; 30,48
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
K P C T K E C G N F A Y G I C P R S E G S P K N P I C T T C C A G Y K G C Y Y Y D A N G K L I C E G


KHCSRNCDSKIAYSKCPGRSEGKTIIKPTGCTTCCTGYKGCYYYGKDDKFVCEG
CSRNC
EGKTI
L-H Type (Type-II)
3,34 ; 7,35 ; 16,31 ; 41,52
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54
K H C S R N C D S K I A Y S K C P G R S E G K T I I K P T G C T T C C T G Y K G C Y Y Y G K D D K F V C E G


DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-30
 111 - 160 50
IRD-68
 49 - 101 53
IRD-283
 142 - 192 51
IRD-472
 25 - 74 50
IRD-503
 83 - 136 54
Amino Acid Count % by Frequency
Alanine 8 4.06
Cysteine 24 12.18
Aspartic acid 9 4.57
Glutamic acid 10 5.08
Phenylalanine 4 2.03
Glycine 19 9.64
Histidine 4 2.03
Isoleucine 8 4.06
Lysine 19 9.64
Leucine 10 5.08
Methionine 3 1.52
Asparagine 8 4.06
Proline 15 7.61
Glutamine 3 1.52
Arginine 8 4.06
Serine 12 6.09
Threonine 15 7.61
Valine 5 2.54
Tryptophan 0 0
Tyrosine 13 6.6