Proteins
  2. Proteins (PIs)
  3. Proteins details
PINIR_82 [Q3S485]  : Proteinase inhibitor II

129Length

Solanum tuberosumSpecie

-Gene Name

13961Mass

3Domain Count

Sequence :
     FASTA
MEHVDAKACT LECGNLGFGI CPRSEGSPEN HICTNCCAGY KGCNYYSANG AFICEGQSDP KKPKACPLNC 70
DPHIAYSKCP RSEGKSLIYP TGCTTCCTGY KGCYYFDKNG KFVCEGESDE PKANMYPAM 129
SIGNAL PEPTIDE
SEQUENCE Position
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
IRD-57
31 - 82 52
IRD-466
7 - 56 50
IRD-495
64 - 116 53
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
5.959
1.4 -7.8 -13.7
CROSS REFERENCES
Uniprot Interpro Id Pfam Id EMBL
Q3S485 View PI in InterPro
IPR003465 		View protein in Pfam
PF02428		 DQ168321
REFERENCES
PubMed ID:    
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-2 CPLNC Chymotrypsin 67 - 71
RL-2 CPLNC Chymotrypsin 67 - 71
RL-9 CTLEC Chymotrypsin 10 - 14
GO TERMS
Molecular Function Cellular Component Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867) None None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
No Records Found
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-57 31 - 82 CPLNC 66 - 70 DPKKP 59 - 63 H-L Type (Type-I)
IRD-466 7 - 56 CTLEC 9 - 13 EGSPE 25 - 29 L-H Type (Type-II)
IRD-495 64 - 116 CPLNC 66 - 70 - H+L Type (Type-III)
HICTNCCAGYKGCNYYSANGAFICEGQSDPKKPKACPLNCDPHIAYSKCPRS
CPLNC
DPKKP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
H I C T N C C A G Y K G C N Y Y S A N G A F I C E G Q S D P K K P K A C P L N C D P H I A Y S K C P R S


KACTLECGNLGFGICPRSEGSPENHICTNCCAGYKGCNYYSANGAFICEG
CTLEC
EGSPE
L-H Type (Type-II)
3,31 ; 7,37 ; 15,27 ; 30,48
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
K A C T L E C G N L G F G I C P R S E G S P E N H I C T N C C A G Y K G C N Y Y S A N G A F I C E G


KACPLNCDPHIAYSKCPRSEGKSLIYPTGCTTCCTGYKGCYYFDKNGKFVCEG
CPLNC
H+L Type (Type-III)
3,33 ; 7,34 ; 16,30 ; 40,51
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53
K A C P L N C D P H I A Y S K C P R S E G K S L I Y P T G C T T C C T G Y K G C Y Y F D K N G K F V C E G


DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-57
 31 - 82 52
IRD-466
 7 - 56 50
IRD-495
 64 - 116 53
Amino Acid Count % by Frequency
Alanine 9 6.98
Cysteine 16 12.4
Aspartic acid 5 3.88
Glutamic acid 9 6.98
Phenylalanine 4 3.1
Glycine 14 10.85
Histidine 3 2.33
Isoleucine 5 3.88
Lysine 11 8.53
Leucine 4 3.1
Methionine 3 2.33
Asparagine 8 6.2
Proline 10 7.75
Glutamine 1 0.78
Arginine 2 1.55
Serine 8 6.2
Threonine 6 4.65
Valine 2 1.55
Tryptophan 0 0
Tyrosine 9 6.98